Laboratory of Cellular Neurobiology of Learning
Brief history and main directions of scientific work of the laboratory
The laboratory was established in 1989 on the basis of a group that conducted research on invertebrate animals, which was part of the laboratory of academician P.V. Simonov. The main directions of scientific work are cellular mechanisms of behavior organization and behavior modifications as a result of learning, cellular and molecular mechanisms of memory. Along with traditional electrophysiological methods, optical methods of recording and confocal microscopy are actively used in the laboratory. As an object of study, animals with a simple nervous system or brain slices of vertebrates are used. International cooperation with Yale University (USA) in the field of optical methods, with the University of Arizona (USA) in the analysis of neural networks of pantopus mollusks, with the Institute of Neurophysiology of the University of Bochum (Germany) and with the University of Connecticut (USA) in the field of synaptic plasticity mechanisms.
Books in English
- Balaban P.M. (2002) Declarative and procedural memory in animals with simple nervous systems. In: "Psychology at the turn of the millennium, Vol. 1: Cognitive, biological, and health perspectives" (Eds: Lars Bäckman & Claes von Hofsten). Psychology Press, pp. 1-28.
- Balaban P.M. Applicability of the reinforcement concept to studies in simple nervous systems. In: Complex Brain Functions. Conceptual Advances in Russian Neuroscience. Eds. A.M.Ivanitsky, P.M.Balaban, Harwood Academic Publishers, 2000, p.201-211.
Список сотрудников
Publication list
Papers
- Samarova E.I., Bravarenko N.I., Korshunova T.A., Gulyaeva N.V., Palotas A., Balaban P.M. Effect of β-amyloid peptide on behavior and synaptic plasticity in terrestrial snail. Brain Research Bulletin. 2005. V. 67. N. 1-2. P. 40-45. DOI: 10.1016/j.brainresbull.2005.05.023
- Samarova E.I., Bravarenko N.I., Korshunova T.A., Gulyaeva N.V., Palotas A., Balaban P.M. Effect of β-amyloid peptide on behavior and synaptic plasticity in terrestrial snail. Brain Research Bulletin. 2005. V. 67. N. 1-2. P. 40-45. DOI: 10.1016/j.brainresbull.2005.05.023
- Samarova E.I., Bravarenko N.I., Korshunova T.A., Gulyaeva N.V., Palotas A., Balaban P.M. Effect of β-amyloid peptide on behavior and synaptic plasticity in terrestrial snail. Brain Research Bulletin. 2005. V. 67. N. 1-2. P. 40-45. DOI: 10.1016/j.brainresbull.2005.05.023
- Storozhuk M.V., Ivanova S.Y., Balaban P.M., Kostyuk P.G. Possible role of mitochondria in posttetanic potentiation of GABAergic synaptic transmission in rat neocortical cell cultures. Synapse. 2005. V. 58. N. 1. P. 45-52. DOI: 10.1002/syn.20186
- Bravarenko N.I., Malyshev A.Y., Voronin L.L., Balaban P.M. Ephaptic feedback in identified synapses of terrestrial snails. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2004. V. 54. N. 4. P. 562-572.
- Gaynutdinova T.K., Tagirova R.R., Ismailova A.I., Muranova L.N., Gaybutdinov L.K., Balaban P.M. Protein synthesis-dependent reactivation of environmental conditioned reflex in terrestrial snails. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2004. V. 54. N. 6. P. 795-800.
- Ivanova Y.L., Leonova O.G., Popenko V.I., Ierusalimsky V.N., Boguslavsky D.V., Balaban P.M., Belyavsky A.V. Immunocytochemical study of the hcs2 gene products distribution in the command neurons of grape snail. Molekulyarnaya Biologiya. 2004. V. 38. N. 6. P. 1024-1032.
- Nikitin E.S., Zakharov I.S., Balaban P.M. Regulation of the length of the snail tentacle by the concentration-dependent contraction. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2004. V. 54. N. 5. P. 655-665.
- Balaban P.M., Chistiakova M., Malyshev A.Y., Volgushev M.A. Dependence of Calcium Influx in Neocortical Cells on Temporal Structure of Depolarization, Number of Spikes, and Blockade of NMDA Receptors. Journal of Neuroscience Research. 2004. V. 76. N. 4. P. 481-487. DOI: 10.1002/jnr.20104
- Balaban P.M., Korshunova T.A., Bravarenko N.I. Postsynaptic calcium contributes to reinforcement in a three-neuron network exhibiting associative plasticity. European Journal of Neuroscience. 2004. V. 19. N. 2. P. 227-233. DOI: 10.1111/j.1460-9568.2003.03129.x
- Marchenko V.G., Pasikova N.V., Kositsyn N.S. Intracortical synchronization of epileptic discharges at different stages of ultrastructural rearrangements in a completely neuronally isolated area of rat neocortex. Neuroscience and Behavioral Physiology. 2004. V. 34. N. 4. P. 307-313. DOI: 10.1023/B:NEAB.0000018737.64204.ca
- Volgushev M.A., Kudryashov I., Chistiakova M., Mukovski M., Niesmann J., Eysel U.T. Probability of transmitter release at neocortical synapses at different temperatures. Journal of Neurophysiology. 2004. V. 92. N. 1. P. 212-220. DOI: 10.1152/jn.01166.2003
- Yousef T., Neubacher U., Eysel U.T., Volgushev M.A. Nitric oxide synthase in rat visual cortex: An immunohistochemical study. Brain Research Protocols. 2004. V. 13. N. 1. P. 57-67. DOI: 10.1016/j.brainresprot.2004.01.004
- Marchenko V.G., Pasikova N.V., Kositsyn N.S. Intracortical synchronization of the epileptiform field potentials at different stages of ultrastructural reorganizations in neuronally isolates island in rats. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2003. V. 53. N. 2. P. 215-221.
- Marchenko V.G., Pasikova N.V., Kositsyn N.S. Sprouting and electrical activity parameters of the sensorimotor rat cortex after damage to the symmetrical portion of the contralateral hemisphere. Doklady Akademii Nauk. 2003. V. 1. N. 3. P. 3-12.
- Moshnikova A.B., Onufriev M.V., Afanasiev V.N., Zhukova A.A., Gulyaeva N.V., Beletsky A.P. Analysis of nuclease sequences in dying and differentiating U-937 cells. Molekuliarnaja Meditsina. 2003. V. 1. P. 52-58.
- Boguslavsky D., Ierusalimsky V.N., Malyshev A.Y., Balaban P.M., Belyavsky A. Selective blockade of gene expression in a single identified snail neuron. Neuroscience. 2003. V. 119. N. 1. P. 15-18. DOI: 10.1016/S0306-4522(03)00075-7
- Bravarenko N.I., Korshunova T.A., Malyshev A.Y., Balaban P.M. Synaptic contact between mechanosensory neuron and withdrawal interneuron in terrestrial snail is mediated by L-glutamate-like transmitter. Neuroscience Letters. 2003. V. 341. N. 3. P. 237-240. DOI: 10.1016/S0304-3940(03)00213-1
- Buzas P., Volgushev M.A., Eysel U.T., Kisvarday Z.F. Independence of visuotopic representation and orientation map in the visual cortex of the cat. European Journal of Neuroscience. 2003. V. 18. N. 4. P. 957-968. DOI: 10.1046/j.1460-9568.2003.02808.x
- Ierusalimsky V.N., Boguslavsky D.V., Belyavsky A.V., Balaban P.M. Helix peptide immunoreactivity pattern in the nervous system of juvenile aplysia. Molecular Brain Research. 2003. V. 120. N. 1. P. 84-89. DOI: 10.1016/j.molbrainres.2003.10.007
- Marchenko V.G., Pasikova N.V., Kositsyn N.S. Sprouting and electrical activity parameters of the rat sensorimotor cortex after damaging a symmetric part of the contralateral hemosphere. Doklady Biological Sciences. 2003. V. 392. P. 391-392.
- Norekyan T.P., Nikitin E.S., Bravarenko N.I., Malyshev A.Y., Balaban P.M. Phase-dependent coordination of two motor programs in the buccal ganglion of a pteropod mollusk. Neuroscience and behavioral physiology. 2003. V. 33. N. 2. P. 107-111. DOI: 10.1023/A:1021757411343
- Balaban P.M. Cellular mechanisms of behavioral plasticity in terrestrial snail. Neuroscience and Biobehavioral Reviews. 2002. V. 26. N. 5. P. 597-630. DOI: 10.1016/S0149-7634(02)00022-2
- Malyshev A.Y., Balaban P.M. Identification of mechanoafferent neurons in terrestrial snail: response properties and synaptic connections. J. Neurophysiol.. 2002. V. 87. N. 5. P. 2364-2371. DOI: 10.1152/jn.00185.2001
- Malyshev A.Y., Norekian T.P. Phase-locked coordination between two rhythmically active feeding structures in the mollusk Clione limacina. I. Motor neurons. Journal of Neurophysiology. 2002. V. 87. N. 6. P. 2996-3005. DOI: 10.1152/jn.2002.87.6.2996
- Norekian T.P., Nikitin E.S., Bravarenko N.I., Malyshev A.Y., Balaban P.M. Phase-dependent coordination of two motor programs in the buccal ganglion of a pteropod mollusk. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2001. V. 51. N. 6. P. 717-722.
- Balaban P.M., Bravarenko N.I., Maksimova O.A., Nikitin E.S., Ierusalimsky V.N., Zakharov I.S. A single serotonergic modulatory cell can mediate reinforcement in the withdrawal network of the terrestrial snail. Neurobiology of Learning and Memory. 2001. V. 75. N. 1. P. 30-50. DOI: 10.1006/nlme.1999.3953
- Balaban P.M., Maksimova O. Decrease of effectivity of 'competing' synaptic input requires protein synthesis. Brain Research. 2001. V. 919. N. 2. P. 318-321. DOI: 10.1016/S0006-8993(01)02895-5
- Balaban P.M., Poteryaev D.A., Zakharov I.S., Uvarov P., Malyshev A.Y., Belyavsky A.V. Up- and down-regulation of Helix command-specific 2 (HCS2) gene expression in the nervous system of terrestrial snail Helix lucorum. Neuroscience. 2001. V. 103. N. 2. P. 551-559. DOI: 10.1016/S0306-4522(01)00004-5
- Bravarenko N.I., Ierusalimsky V.N., Korshunova T.A., Malyshev A.Y., Zakharov I.S., Balaban P.M. Participation of GABA in establishing behavioral hierarchiesin the terrestrial snail. Experimental Brain Research. 2001. V. 141. N. 3. P. 340-348. DOI: 10.1007/s002210100886
- Bravarenko N.I., Ierusalimsky V.N., Korshunova T.A., Malyshev A.Y., Zakharov I.S., Balaban P.M. Participation of GABA in establishing behavioral hierarchiesin the terrestrial snail. Experimental Brain Research. 2001. V. 141. N. 3. P. 340-348. DOI: 10.1007/s002210100886
- Ezrokhi V.L., Kas'yanov A.M., Markevich V.A., Balaban P.M. Reverberation of excitation in living "hippocampal formation-entorhinal cortex" slices from rats. Optical recording. Neuroscience and Behavioral Physiology. 2001. V. 31. N. 1. P. 31-37. DOI: 10.1023/A:1026618129064
- Ierusalimsky V.N., Balaban P.M. Ontogenesis of the snail, Helix aspersa: Embryogenesis timetable and ontogenesis of GABA-like immunoreactive neurons in the central nervous system. Journal of Neurocytology. 2001. V. 30. N. 1. P. 73-91. DOI: 10.1023/A:1011921525359
- Loseva E.V., Vorobiev V.N., Alekseeva T.G., Ermakova I.V., Zakharov I.S., Lermontova N.N., Balaban P.M. Development of neuronal ganglion xenografts from gastropoda in rat brain. Bulletin of Experimental Biology and Medicine. 2001. V. 132. N. 1. P. 689-694. DOI: 10.1023/A:1012592631552
- Loseva E.V., Vorobyev V.N., Ermakova I.V., Lermontova N.N., Alekseeva T.G., Zakharov I.S., Balaban P.M. Comparison of reactive processes in the rat brain elicited by xenotransplantation of nervous tissues of chicken or pulmonate snail. Brain Research. 2001. V. 915. N. 2. P. 125-132. DOI: 10.1016/S0006-8993(01)02908-0
- Nikitin E.S., Balaban P.M. Optical recording of responses to odor in olfactory structures of the nervous system in the terrestrial mollusk Helix. Neuroscience and Behavioral Physiology. 2001. V. 31. N. 1. P. 21-30. DOI: 10.1023/A:1026666012225
- Pasikova N.V., Marchenko V.G., Kositsyn N.S. Structural bases of intracortical processes underlying the synchronization of epileptic potentials in the sensorimotor areas of the neocortex in rats. Neuroscience and Behavioral Physiology. 2001. V. 31. N. 5. P. 497-501. DOI: 10.1023/A:1010470730416
- Ivanova V.O., Martynova O.V., Aleynik S.V., Limarenko A.V. Effect of modified SHF and acoustic stimulation on spectral characteristics of the electroencephalograms of the cat brain. Biofizika. 2000. V. 45. P. 935-940.
- Orlova M.E., Zakharov I.S., Balaban P.M. The participation of GFAD-synthesizing neurons in behavior regulation in the snail (Helix lucorum L.). Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2000. V. 50. N. 1. P. 113-123.
- Pasikova N.V., Marchenko V.G., Kositsyn N.S. Structural basis of processes of intracortical synchronization of epileptic potentials in the sensorimotor region of rat neocortex. Rossijskij Fiziologicheskij Zhurnal im I M Sechenova. 2000. V. 86. N. 5. P. 532-540.
- Moroz L.L., Norekian T.P., Pirtle T.J., Robertson K.J., Satterlie R.A. Distribution of NADPH-diaphorase reactivity and effects of nitric oxide on feeding and locomotory circuitry in the pteropod mollusc, Clione limacina. Journal of Comparartive Neurology. 2000. V. 427. N. 2. P. 274-284.
- Nikitin E.S., Balaban P.M. Optical recording of odor-evoked responses in the olfactory brain of the naive and aversively trained terrestrial snails. Learning and Memory. 2000. V. 7. N. 6. P. 422-432. DOI: 10.1101/lm.32500
- Pasikova N.V., Marchenko V.G., Kositsyn N.S. An improved method for isolating parts of the rat neocortex. Neuroscience and Behavioral Physiology. 2000. V. 30. N. 4. P. 427-429. DOI: 10.1007/BF02463097
- Satterlie R.A., Norekian T.P., Pirtle T.J. Serotonin-induced spike narrowing in a locomotor pattern generator permits increases in cycle frequency during accelerations. Journal of Neurophysiology. 2000. V. 83. N. 4. P. 2163-2170.
- Volgushev M.A., Balaban P.M., Chistiakova M., Eysel U.T. Retrograde signalling with nitric oxide at neocortical synapses. European Journal of Neuroscience. 2000. V. 12. N. 12. P. 4255-4267. DOI: 10.1046/j.0953-816X.2000.01322.x
- Volgushev M.A., Vidyasagar T.R., Chistiakova M., Eysel U.T. Synaptic transmission in the neocortex during reversible cooling. Neuroscience. 2000. V. 98. N. 1. P. 9-22. DOI: 10.1016/S0306-4522(00)00109-3
- Nikitin E.S., Balaban P.M. Optical recording of the odor-evoked responses in olfactory structures of the brain of the terrestrial mollusk Helix. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 1999. V. 49. N. 5. P. 817-829.
- Pasikova N.V., Marchenko V.G., Kositsyn N.S. An improved method for isolating a section of the rat neocortex. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 1999. V. 49. N. 2. P. 355-358.
- Pasikova N.V., Marchenko V.G., Kositsyn N.S. Improvement and use of the method of isolation of a small animal neocortex site for long-term studies. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 1999. V. 49. N. 2. P. 354-357.
- Pasikova N.V., Nozdrachev L.V., Marchenko V.G., Kositsyn N.S. The dynamics of the activity of respiratory enzymes in neuronally isolated and symmetrical parts of rat neocortex. Bulleten Informatsionnoj meditsiny. 1999. V. 127. N. 2. P. 143-145.