Natalia V. Gulyaeva

Chief of the Department, D.Sc. in Biology, Prof.

molecular basis of disease, animal models, behaviour, glucocorticoid signaling, neurogenesis, neuroinflammation, neuronal plasticity, neuropeptides, stress, dementia, depression, epilepsy, stroke, traumatic brain injury, neurodegenerative diseases

Laboratory of Functional Biochemistry of the Nervous System
Scopus ID
35571299800
ORCID ID
0000-0002-5380-7954
Web of Science ResearcherID
R-7959-2016
SPIN code
4807-1036

Publication list

Papers

  • Stepanichev M.Y., Moiseeva Y.V., Lazareva N.A., Onufriev M.V., Gulyaeva N.V. Single intracerebroventricular administration of amyloid-beta (25-35) peptide induces impairment in short-term rather than long-term memory in rats. Brain Research Bulletin. 2003. V. 61. N. 2. P. 197-205. DOI: 10.1016/S0361-9230(03)00118-7
  • Stepanichev M.Y., Zdobnova I.M., Yakovlev A.A., Onufriev M.V., Lazareva N.A., Zarubenko I.I., Gulyaeva N.V. Effects of tumor necrosis factor-alpha central administration on hippocampal damage in rat induced by amyloid beta-peptide (25-35). Journal of Neuroscience Research. 2003. V. 71. N. 1. P. 110-120. DOI: 10.1002/jnr.10469
  • Terenina N.B., Onufriev M.V., Gulyaeva N.V., Moiseeva Y.V., Gustafsson M.K. Nitric oxide synthase activity in Fasciola hepatica: a radiometric study. Parasitology. 2003. V. 126. N. 6. P. 585-590.
  • Trubetskaya V.V., Stepanichev M.Y., Onufriev M.V., Lazareva N.A., Markevich V.A., Gulyaeva N.V. Administration of aggregated beta-amyloid peptide (25-35) induces changes in long-term potentiation in the hippocampus in vivo. Neuroscience and behavioral physiology. 2003. V. 33. N. 2. P. 95-98. DOI: 10.1023/A:1021761310435
  • Adiatullin A.I., Gulyaeva N.V. The influence of the natural biocorrector Namivite on free radical processes in abdominal delivery. Bulleten Esperimentalnoj biologii i meditsiny. 2002. V. 134. P. 532-534.
  • Egorova L.K., Stepanichev M.Y., Mikhalev S.L., Kutepova O.A., Gulyaeva N.V. Analysis of cyclic adenosine-3',5'-monophosphate levels in structures of the "informational" and "motivational" systems of the rat brain during acquisition of a conditioned active avoidance reaction. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2002. V. 52. P. 235-240.
  • Zdobnova I.M., Stepanichev M.Y., Yakovlev A.A., Onufriev M.V., Egorova L.K., Moiseeva Y.V., Lazareva N.A., Matz V.N., Gulyaeva N.V. The interaction of the neurotoxic fragment of the beta-amyloid peptide and tumor necrosis factor alpha with intracerebral administration to rats. Nejrokhimija. 2002. V. 19. P. 117-122.
  • Onufriev M.V., Semenova T.P., Kopaeva S.G., Moiseeva Y.V., Egorova L.K., Gulyaeva N.V. Nitric oxide synthase activity in the brain regions of Citellus undulatus gophers in different phases of the hibernation cycle. Nejrokhimija. 2002. V. 19. P. 264-268.
  • Pavlova I.V., Yakovlev A.A., Stepanichev M.Y., Mendzheritsky A.M., Gulyaeva N.V. Pentylenetetrazole Kindling causes oxidative stress in rat brain. Nejrokhimija. 2002. V. 19. P. 123-126.
  • Stepanichev M.Y., Moiseeva Y.V., Gulyaeva N.V. "Injection" models of Alzheimer's disease: oxidative stress in the toxicity mechanism of AF64A and β-amyloid peptide in rodents. Nejrokhimija. 2002. V. 19. P. 165-175.
  • Khaspekov L.G., Onufriev M.V., Lyzhin A.A., Viktorov I.V., Gulyaeva N.V. The dynamics of proteolytic activity associated with caspase-3, with ischemic effects on cultured rat cerebellum grain cells. Nejrokhimija. 2002. V. 19. P. 37-40.
  • Yakovlev A.A., Semenova T.P., Kolaeva S.G., Onufriev M.V., Mikhalea S.L., Gulyaeva N.V. Change in caspase-3 activity in the brain regions of gophers of Citellus undulatus during the hibernation cycle. Nejrokhimija. 2002. V. 19. 33-36.
  • Adiyatulin A.I., Gulyaeva N.V. Effect of natural biocorrector namivit on free-radical processes in abdominal delivery. Bulletin of Experimental Biology and Medicine. 2002. V. 134. N. 5. P. 457-459. DOI: 10.1023/A:1022690330562
  • Kudryashov I.E., Yakovlev A.A., Kudryashova I.V., Gulyaeva N.V. Footshock stress alters early postnatal development of electrophysiological responses and caspase-3 activity in rat hippocampus. Neuroscience Letters. 2002. V. 332. N. 2. P. 95-98. DOI: 10.1016/S0304-3940(02)00937-0
  • Bolshakov A.P., Onufriev M.V., Khanicheva N.A., Stepanichev M.Y., Chabak-Garbach R.., Ajrapetiantz M.G., Gulyaeva N.V. Effect of early social isolation on nitric oxide synthase activity in rat brain. Nejrokhimija. 2001. V. 18. P. 262-266.
  • Moiseeva Y.V., Onufriev M.V., Lazareva N.A., Stepanichev M.Y., Gulyaeva N.V. Free-radical mechanisms of septo-hippocampal neurodegeneration caused by cholinotoxin AF64A in rats in vivo. Nejrokhimija. 2001. V. 18. P. 287-289.
  • Trubetskaya V.V., Stepanichev M.Y., Onufriev M.V., Lazareva N.A., Markevich V.A., Gulyaeva N.V. Administration of aggregated beta-amyloid peptide (25-35) causes change in long-term potentiation in the hippocampus. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2001. V. 51. N. 6. P. 690-693.
  • Trubetskaya V.V., Stepanichev M.Y., Onufriev M.V., Lazareva N.A., Markevich V.A., Gulyaeva N.V. Increase in activity of NO-synthetase in rat's hippocampus follows long-term potentiation in vivo. Nejrokhimiya. 2001. V. 18. N. 1. P. 55-61.
  • Trubetskaya V.V., Stepanichev M.Y., Onufriev M.V., Lazareva N.A., Markevich V.A., Gulyaeva N.V. Administration of aggregated beta-amyloid peptide (25-35) induces changes in long-term potentiation in hippocampus in vivo. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2001. V. 51. N. 6. P. 701-704.
  • Trubetskaya V.V., Stepanichev M.Y., Onufriev M.V., Lazareva N.A., Markevich V.A., Gulyaeva N.V. Increased NO synthase activity in rat hippocampus accompanies prolonged in vivo potentiation. Nejrokhimija. 2001. V. 18. P. 55-61.
  • Tsubetskaya V.V., Stepanichev M.Y., Onufriev M.V., Lazareva N.A., Markevich V.A., Gulyaeva N.V. Administration of aggregated beta-amyloid peptide (25–35) induces changes in long-term potentiation in the hippocampus in vivo. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 2001. V. 51. P. 701-704.
  • Yakovlev A.A., Onufriev M.V., Stepanichev M.Y., Braun K.., Gulyaeva N.V. Caspase-3 activity in different parts of the brain of rodents. Nejrokhimija. 2001. V. 18. P. 41-43.
  • Yakovlev A.A., Onufriev M.V., Stepanichev M.Y., Gulyaeva N.V. The effect of pentylenetetrazole on caspase-3 activity in the brain regions of mice. Nejrokhimija. 2001. V. 18. P. 191-194.
  • Kudryashov I.E., Onufriev M.V., Kudryashova I.V., Gulyaeva N.V. Periods of postnatal maturation of hippocampus: Synaptic modifications and neuronal disconnection. Developmental Brain Research. 2001. V. 132. N. 2. P. 113-120. DOI: 10.1016/S0165-3806(01)00301-7
  • Melnik V.I., Bikbulatova L.S., Gulyaeva N.V., Bazyan A.S. Synaptic vesicle acidification and exocytosis studied with acridine orange fluorescence in rat brain synaptosomes. Neurochemical Research. 2001. V. 26. N. 5. P. 549-554. DOI: 10.1023/A:1010973214930
  • Bikbulatova L.S., Melnik V.I., Gulyaeva N.V., Bazyan A.S. Acridinorange as a fluorescent probe for the study of acidification and exocytosis of synaptic vesicles in synaptosomes. Nejrokhimija. 2000. V. 17. P. 303-308.
  • Khaspekov L.G., Onufriev M.V., Viktorov I.V., Gulyaeva N.V. The effect of ischemia and reoxygenation on the accumulation of nitrites in rat cerebellum grain cell cultures. Nejrokhimija. 2000. V. 17. P. 267-270.
  • Bobrysheva I.V., Chernyavskaya L.I., Onufriev M.V., Grivennikov I.A., Gulyaeva N.V. Hydrogen peroxide dose-dependently inhibits caspase-3 in PC12 cells. Nejrokhimija. 2000. V. 17. P. 93-98.
  • Lautenschlager M., Onufriev M.V., Gulyaeva N.V., Harms C., Freyer D., Sehmsdorf U.-., Ruscher K., Moiseeva Y.V., Arnswald A., Victorov I., Dirnagl U., Weber J.R., Hortnagl H. Role of nitric oxide in the ethylcholine aziridinium model of delayed apoptotic neurodegeneration in vivo and in vitro. Neuroscience. 2000. V. 97. N. 2. P. 383-393. DOI: 10.1016/S0306-4522(99)00599-0
  • Lautenschlager M., Onufriev M.V., Gulyaeva N.V., Harms C., Freyer D., Sehmsdorf U.-., Ruscher K., Moiseeva Y.V., Arnswald A., Victorov I., Dirnagl U., Weber J.R., Hortnagl H. Role of nitric oxide in the ethylcholine aziridinium model of delayed apoptotic neurodegeneration in vivo and in vitro. Neuroscience. 2000. V. 97. N. 2. P. 383-393. DOI: 10.1016/S0306-4522(99)00599-0
  • Onufriev M.V., Terenina N.B., Lindholm A.M., Reuter M., Gustafsson M.K., Gulyaeva N.V. Neuronal form of nitric oxide synthase activity in Hymenolepis diminuta (Cestoda: Pseudophyllidae). Nejrokhimija. 2000. V. 17. P. 37-41.
  • Poeggel G., Haase C., Gulyaeva N.V., Braun K. Quantitative changes in reduced nicotinamide adenine dinucleotide phosphate-diaphorase-reactive neurons in the brain of Octodon degus after periodic maternal separation and early social isolation. Neuroscience. 2000. V. 99. N. 2. P. 381-387. DOI: 10.1016/S0306-4522(00)00190-1
  • Stepanichev M.Y., Onufriev M.V., Bock J., Gulyaeva N.V., Poeggel G., Braun K. Changes of nitric oxide synthase activity in response to different levels of social separation in two day old domestic chicks (Gallus gallus domesticus). Neuroscience Research Communications. 2000. V. 27. P. 175-181.
  • Stepanichev M.Y., Onufriev M.V., Mitrokhina O.S., Moiseeva Y.V., Lazareva N.A., Victorov I.V., Gulyaeva N.V. Neurochemical, behavioral, and neuromorphological effects of central administration of beta-amyloid peptide (25-35) in rat. Nejrokhimija. 2000. V. 17. P. 278-290.
  • Stepanichev M.Y., Zdobnova I.M., Zarubenko I.I., Lazareva N.A., Onufriev M.V., Moiseeva Y.V., Chernyavskaya L.I., Gulyaeva N.V. Seizure intensity correlates with oxidative stress and apoptosis in the hippocampus in the kainic acid model in rat. Nejrokhimija. 2000. V. 17. P. 189-191.
  • Terenina N.B., Onufriev M.V., Gulyaeva N.V., Lindholm A.M., Gustafsson M.K. A radiometric analysis of nitric oxide synthase activity in Hymenolepis diminuta. Parasitology. 2000. V. 120. N. 1. P. 91-95. DOI: 10.1017/S0031182099005284
  • Gulyaeva N.V., Brusovanik V.I., Lazareva N.A., Libe M.L., Mikhalev S.L., Onufriev M.V., Chernyavskaja L.I. Indices of free radical oxidation in plasma of umbilical cord blood and placenta of residents of Altai Territory. Izvestija Academii nauk, serija biologicheskaja. 1999. V. 1. N. 4. P. 453-457.
  • Mitrokhina O.S., Stepanichev M.Y., Lazareva N.A., Moiseeva Y.V., Onufriev M.V., Gulyaeva N.V. The effect of intracerebroventricular administration of a fragment (25-35) of beta-amyloid peptide on lipid peroxidation in rat brain and blood. Doklady Akademii Nauk. 1999. V. 368. P. 711-713.
  • Moiseeva Y.V., Egorova L.K., Onufriev M.V., Mitrokhina O.S., Lazareva N.A., Stepanichev M.Y., Gulyaeva N.V. NO synthase activity and indicators of free radical oxidation in the brain regions of Wistar rats resistant and prone to audiogenic epilepsy: effects of immobilization stress. Nejrokhimija. 1999. V. 16. P. 54-61.
  • Onufriev M.V., Stepanichev M.Y., Mitrokhina O.S., Moiseeva Y.V., Lazareva N.A., Gulyaeva N.V. The effect of oxidative stress on the activity of nitric oxide synthase in vivo and in vitro. Rossijskoj Fiziologicheskij Zhurnal. 1999. V. 85. P. 531-538.
  • Rozhnova U.A., Stepanichev M.Y., Korobko V.G., Gulyaeva N.V., Alesenko A.V. Activation of the sphingomoelin cycle and cholesterol accumulation in rat cortex, hippocampus and cerebellum under the action of tumor necrosis factor alpha. Nejrokhimija. 1999. V. 16. 118-131.
  • Stepanichev M.Y., Onufriev M.V., Lazareva N.A., Zarzhetsky Y.V., Mutuskina E.A., Gurvich A.M., Gulyaeva N.V. Delayed effects of systemic circulatory arrest on free radical processes in the brain structures of rats with different types of behavior in the emotional resonance test. Zhurnal Vysshei Nervnoi Deiatelnosti im I P Pavlova. 1999. V. 49. P. 653-663.
  • Poeggel G., Lange E., Hase C., Metzger M., Gulyaeva N.V., Braun K. Maternal separation and early social deprivation in octodon degus: Quantitative changes of nicotinamide adenine dinucleotide phosphate-diaphorase-reactive neurons in the prefrontal cortex and nucleus accumbens. Neuroscience. 1999. V. 94. N. 2. P. 497-504. DOI: 10.1016/S0306-4522(99)00289-4
  • Rakusan K., Ehrenburg I.V., Gulyaeva N.V., Tkatchouk E.N. The effect of intermittent normobaric hypoxia on vascularization of human myometrium. Microvascular Research. 1999. V. 58. N. 2. P. 200-203. DOI: 10.1006/mvre.1999.2180
  • Silkis I.G., Egorova L.K., Markevich V.A., Gulyaeva N.V. On the participation of GABAb receptors in the formation of cGMP in the cerebellar cortex. Nejrokhimija. 1998. V. 15. N. 4. P. 335-400.
  • Stepanichev M.Y., Lazareva N.A., Onufriev M.V., Mitrokhina O.S., Moiseeva Y.V., Gulyaeva N.V. Effects of doses of fragment (25-35) of β-amyloid peptide on behavior in rats. Neuroscience and Behavioral Physiology. 1998. V. 28. N. 5. P. 564-566. DOI: 10.1007/BF02463018
  • Gulyaeva N.V., Stepanichev M.Y. Biochemical correlates of individual behavior. Neuroscience and Behavioral Physiology. 1997. V. 27. N. 4. P. 462-469. DOI: 10.1007/BF02462948
  • Gurvitch A.M., Mutuskina E.A., Zarzhetsky Y.V., Trubina I.E., Avruschenko M.S., Pylova S.I., Volkov A.V., Lazareva N.A., Stepanichev M.Y., Onufriev M.V., Gulyaeva N.V. Prophylaxis of encephalopathies and risk factors of atherogenesis development in the postresuscitation period in rats by means of succinic acid. Resuscitation. 1997. V. 35. N. 2. P. 165-170. DOI: 10.1016/S0300-9572(97)00045-2
  • Stepanichev M.Y., Onufriev M.V., Lazareva N.A., Zazhetsky Y.V., Mutuskina E.A., Gutvitch A.M., Gulyaeva N.V. Postresuscitation changes in brain free radical-mediated processes and nitric oxide synthase activity in rats: effects of individual behavior in "emotional resonance" test. Neurochemical Research. 1997. V. 22. N. 6. P. 743-752.
  • Gulyaeva N.V., Lazareva N.A., Libe M.L., Mitrokhina O.S., Onufriev M.V., Stepanichev M.Y., Chernysevskaya I.A., Walsh T.J. Oxidative stress in the brain following intraventricular administration of ethylcholine aziridinium (AF64A). Brain Research. 1996. V. 726. N. 1-2. P. 174-180. DOI: 10.1016/0006-8993(96)00330-7