Institute of Higher Nervous Activity and Neurophysiology of RAS

5A Butlerova St., Moscow 117485, Russia

Tel.: +7 495 3347000
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Europe spent €600 million to recreate the human brain in a computer. How did it go?
The Human Brain Project wraps up in September after a decade. Nature examines its achievements and its troubled past.

A 25-Year-Old Bet about Consciousness Has Finally Been Settled
A brain scientist and a philosopher have resolved a wager on consciousness that was made when Bill Clinton was president

Why Conscious AI Is a Bad, Bad Idea
Our minds haven’t evolved to deal with machines we believe have consciousness

Semantic reconstruction of continuous language from non-invasive brain recordings
A brain–computer interface that decodes continuous language from non-invasive recordings would have many scientific and practical applications

Exploring the mechanisms of consciousness disorders'
Brain Matters #14

Holding information in mind may mean storing it among synapses
Comparing models of working memory with real-world data, MIT researchers found that information resides not in persistent neural activity, but in the pattern of their connections

New version of Arbor neural network simulation library released
Arbor is a multi-compartment neural network simulation library designed to be portable across contemporary high-performance computing architectures. The most recent version is now available on EBRAINS

Coordinated multiplexing of information about separate objects in visual cortex
Sensory receptive fields are large enough that they can contain more than one perceptible stimulus

HBP researchers map the 'synaptic landscape' of a cognitive nucleus of the thalamus
Researchers from the Autonomous University of Madrid (UAM) supported by the Human Brain Project (HBP) were able for the first time to identify the origin, intranuclear distribution and size of all types of axon terminals present in a cognitive nucleus of the thalamus

A ubiquitous spectrolaminar motif of local field potential power across the primate cortex
The spectrolaminar pattern characterized by an increasing deep-to-superficial layer gradient of gamma frequency LFP power peaking in layers 2/3, and an increasing superficial-to-deep gradient of alpha-beta power peaking in layers 5/6

Most detailed map of brain’s memory hub finds connectivity puzzle
Fewer links uncovered to frontal lobes, but more to visual networks

Illuminating a mysterious brain structure
Neuroscientists are shedding literal light on the mouse claustrum, a tiny part of the brain with an outsized number of connections

STEPS 4.0 towards large-scale biologically-relevant simulations
Simulating neurons down to the level of their biochemistry in order to understand their behavior and properties is a complex computational challenge

A mind-body interface alternates with effector-specific regions in motor cortex
Researchers have identified the Mind-Body Interface, a novel distributed network within human primary motor cortex that disrupts the famous but incorrect motor homunculus, and that exhibits strong connections to high-level control networks

Mapping neurotransmitter systems to the structural and functional organization of the human neocortex
There are collate positron emission tomography data from more than 1,200 healthy individuals to construct a whole-brain three-dimensional normative atlas of 19 receptors and transporters across nine different neurotransmitter systems.

A new way to merge electro/magnetoencephalography and tractography to measure conduction delays in multiple sclerosis
Researchers of the Human Brain Project have developed a new methodology to calculate the delay of signal propagations in brains of patients

Large-scale waves of activity in the neonatal mouse brain in vivo occur almost exclusively during sleep cycles
Spontaneous electrical activity plays major roles in the development of cortical circuitry. This activity can occur highly localized regions or can propagate over the entire cortex. Both types of activity coexist during early development

NSG Virtual workshop
The Neuroscience Gateway (NSG) will host a Virtual workshop as a part of the Society for Neuroscience Annual Meeting in San Diego, November 2022

eLife’s New Model: Changing the way you share your research
From next year, eLife is eliminating accept/reject decisions after peer review, instead focusing on public reviews and assessments of preprints

Meta-connectomic analysis maps consistent, reproducible, and transcriptionally relevant functional connectome hubs in the human brain
Here, we conduct a worldwide harmonized meta-connectomic analysis by pooling resting-state functional MRI data of 5212 healthy young adults across 61 independent cohorts

How the brain focuses on what’s in mind
When holding information in mind, neural activity is more focused when and where there are bursts of gamma frequency rhythms

How the brain generates rhythmic behavior
MIT neuroscientists have identified an oscillatory circuit that controls the rhythmic movement of mouse whiskers

Constructive connectomics: How neuronal axons get from here to there using gene-expression maps derived from their family trees
During brain development, billions of axons must navigate over multiple spatial scales to reach specific neuronal targets, and so build the processing circuits that generate the intelligent behavior of animals

When Alzheimer’s degrades cells that cross hemispheres, visual memory suffers
Cross-hemisphere interactions are suddenly getting interesting after decades of neglect

This Man Set the Record for Wearing a Brain-Computer Interface
Implanted devices let people control computers and prosthetic limbs with their minds. But nobody knows how long they’ll last—and when they’ll need upgrades

EBRAINS Brain Atlas enables researchers to gain a deeper understanding of brain organization
The study demonstrates a method to unravel structure-function relationships by using the multilevel Julich-Brain Atlas on EBRAINS to bridge the different scales of brain organisation. The findings provide insight into the visual, auditory, somatosensory, and motor systems of the brain

The brain processes behind pattern recognition
Human brains learn patterns over time and we don’t even realize it. New insight into how this works could improve learning and other cognitive processes

The End of Baldness? The Chemical Controlling Life and Death in Hair Follicles Identified
A single chemical is key to controlling when hair follicle cells divide, and when they die. This discovery could not only treat baldness, but ultimately speed wound healing because follicles are a source of stem cells.

Patterned Hippocampal Stimulation Facilitates Memory in Patients With a History of Head Impact and/or Brain Injury
Deep brain stimulation (DBS) of the hippocampus for enhancement of memory impaired by injury or disease

10 place cells recorded simultaneously over 50 minutes of foraging
Rat hippocampus CA1

A Relativistic Theory of Consciousness
Consciousness can not simply be reduced to neural activity alone. A novel study reports the dynamics of consciousness may be understood by a newly developed conceptual and mathematical framework.

Anesthetic drastically diverts the travels of brain waves
Under propofol general anesthesia very slow frequency traveling waves transform and dominate

‘Traveling’ nature of brain waves may help working memory work
The act of holding information in mind is accompanied by coordination of rotating brain waves in the prefrontal cortex, a new study finds

New study reveals how brain waves control working memory
Brain rhythms act as a gate for information entering and leaving the mind

New method spotlights synaptic plasticity in living mice
Using a new line of mice that express a synaptic membrane receptor with a fluorescent tag, researchers have tracked changes in the strength of synapses across the brain over several days

Visual and linguistic semantic representations are aligned at the border of human visual cortex
These results suggest that these two networks are smoothly joined to form one contiguous map

Researchers predict rat behaviors from brain activity
If behavior is a language, neuroscientist is decoding its grammar.

How the world’s biggest brain maps could transform neuroscience
Scientists around the world are working together to catalogue and map cells in the brain. What have these huge projects revealed about how it works?

Digital Reconstruction of Neocortical Microcircuitry
Visualizations of the first square millimeter of simulated rat brain


Neural Plasticity Depends On This Long Noncoding RNA’s Journey From Nucleus to Synapse
Study sheds new light on the role noncoded RNAs play at the synapse

How Neural Systems Process and Store Information
A single neuron is able to select between different patterns, dependent upon the properties of individual stimuli

Genetic Predisposition to Schizophrenia May Increase Risk of Psychosis From Cannabis Use
While cannabis users reported more psychotic experiences than non-users generally, the effect was more pronounced in those with a genetic risk factor for schizophrenia

The Neural Basis of Psychopathy
Neuroimaging study reveals structural and functional differences in brain areas associated with emotional regulation in those with personality traits linked to psychopathy or antisocial personality disorder

How Spanking May Affect Brain Development in Children
Corporal punishment may detrimentally harm brain development, a new study reports

Study Showing How the Brain Retrieves Facts and May Help People With Memory Problems
A shared set of brain regions play a vital role in the retrieval of weak memories

Autism Gene Study Finds Widespread Impact to Brain’s Growth Signaling Network
Mutations in the autism-related Dyrk1a gene lead to brain undergrowth in mice

Chronic Sinus Inflammation Appears to Alter Brain Activity
Researchers link the inflammation associated with chronic sinus infections to alterations in brain activity in networks that govern cognition, external stimuli, and introspection

A Blood Test For Depression and Bipolar Disorder
A new blood test can distinguish the severity of a person’s depression and their risk for developing severe depression at a later point

Key Brain Molecule May Play Role in Many Brain Disorders
miRNA29 is a key cellular switch in controlling late-stage brain development

Leptin Puts the Brakes on Eating via Novel Neurocircuit
Researchers have identified novel neurocircuitry between midbrain structures which are modulated by leptin to control eating behaviors in mice

Study Links Prenatal Phthalate Exposure to Altered Information Processing in Infants
Fetal exposure to phthalates alters cognitive processing in young children, a new study reports. Children whose mothers were exposed to higher levels of phthalates during pregnancy exhibited slower information processing skills. Male children were most likely to experience difficulties

Outside Factors May Help Children Develop Internal Control
A new theory proposes executive function, or the ability to control your behavior, might not exist just within the mind. External influences may dictate the development of internal control

New Blueprint of Brain Connections Reveals Extensive Reach of Central Regulator
A new map of the basal ganglia provides a blueprint of the structure of the brain region and reveals a new level of influence connected to this area

Vitamins for Your Neurons
All-trans retinoic acid, a vitamin A derivative, induces synaptic plasticity in human cortical neurons

‘Zombie’ Genes? Some Genes Come to Life in the Brain After Death
In the hours after death, some cells in the human brain not only remain active, they grow in size

Neuroscience Basics
IHNA starts the theoretical course

event 12.12.2020

XXIII scientific school-conference of young scientists on the physiology of higher nervous activity and neurophysiology

A centerpiece of the 3-D human brain atlas published
Human Brain Project

Brain Thickness and Connectivity, Not Just Location, Correlates With Behavior
Cortical thickness and regional brain connectivity pay an equally important role in linking brain and behavior

Why the Brain Never Processes the Same Input in the Same Way
Depending on the network state, certain neurons in the primary somatosensory cortex can be more or less excitable, which shapes stimulus processing in the brain

Scientists Observe Learning Processes Online in the Brain
Repeatedly administered tactile simulation over a sustained period of time alters neural processing of the hand area in the brain. The observable changes over time illustrate neuroplasticity and shed new light on the process of learning

Discovery of “Thought Worms” Opens Window to the Mind
Researchers have discovered a brain-based marker for new thoughts, reporting people experience more than 6,000 thoughts per day. The study reports a new method that can detect indirectly when one thought ends and another begins

Is What I See, What I Imagine? The Neural Overlap Between Vision and Imagination
Using artificial intelligence and neuroimaging, researchers have identified a link between mental imagery and vision. The brain uses similar visual areas for mental imagery and vision but uses low-level visual areas less precisely for mental imagery than vision

Brain ‘Signature’ Could Help to Diagnose Schizophrenia
An EEG study reveals people with schizophrenia and their siblings without the disorder share patterns of brain activity that are different from people with no familial history of schizophrenia

Brain Structural Elements in Psychiatric Disorders
Comparing data from multiple neuroimaging studies, researchers found shared brain structural abnormalities between four psychiatric disorders, including schizophrenia and bipolar disorder. They also identified brain signatures unique to each condition

New imaging method tracks brain’s elusive networks
A new system for high-density EEG helps with the imaging of the origin and path of both normal and abnormal neural activity

Neuroscientists Think They've Found a Previously Unknown Form of Neural Communication
Scientists think they've identified a previously unknown form of neural communication that self-propagates across brain tissue, and can leap wirelessly from neurons in one section of brain tissue to another – even if they've been surgically severed

Dynamic stimulation of the visual cortex allows blind and sighted people to ‘see’ shapes
A visual cortical prosthesis can restore sight by bypassing damage to the eyes and delivering visual information retrieved from a camera directly to the brain

Significant differences exist among neurons expressing dopamine receptors
Dopamine receptors have different molecular features and functions depending on their anatomical location within the striatum

How strong is your mental imagery? It might depend on how ‘excitable’ your neurons are
Highly excitable neurons in the visual cortex may reduce a person’s ability to imagine mental images

High density EEG produces dynamic image of brain signal source
Researchers combine machine learning, EEG, and new functional imaging technology to dynamically map a neural signal’s source and underlying brain networks

Origins of human language pathway in the brain at least 25 million years old
Studying auditory regions and brain pathways in humans, apes, and monkeys, researchers have identified a language pathway that interconnects the auditory cortex with frontal lobe regions

A gut-to-brain circuit drives sugar preference and may explain sugar cravings
In the intestines, signals of sugar ingestion travel to the brain, sparking an appetite for more sweet foods

Advanced, high-res MRI scans reveal link between cognitive abilities and ‘tree ring’ layers in the brain
Object and facial recognition abilities are associated with the same brain area but are characterized by different depths of cortical layers, which form at the age each ability was acquired.

NIH BRAIN Initiative tool helps researchers watch neural activity in 3D
SCAPE microscopy, a new 3D imaging technique, allows a greater volume of brain tissue to be viewed in a much less damaging way to networks of living cells

The brain dictionary
Scientists have created an interactive map showing which brain areas respond to hearing different words

This is a 100 micron resolution magnetic resonance imaging (MRI) scan of an ex vivo human brain specimen

Home Featured Rhythmic control of ‘brain waves’ can boost memory
Memory performance can be enhanced by rhythmic neural stimulation, using both invasive and non-invasive techniques

The scientific case for brain simulations
Researchers report a need for open, general purpose simulation engines that can run different models of the brain at different levels of biological detail

Neuroimaging reveals a significantly diminished response in the ventromedial prefrontal cortex in children on the autism spectrum

Specific angles and sharpness of brain waves seen in unfiltered raw data from scalp electroencephalograms have been tied to Parkinson’s disease (University of Oregon)

Functional connectivity problems associated with temporal lobe epilepsy appear to improve after surgery

Studying brain tissue samples from people with ASD revealed a common set of alterations in genes associated with synaptic communication between neurons

Researchers present a new model that may explain the flexibility of working memory

A BK channel–mediated feedback pathway links single-synapse activity with action potential sharpening in repetitive firing
A novel short-term presynaptic plasticity mechanism

Analysis of shared heritability in common disorders of the brain
Brain disorders may exhibit shared symptoms and substantial epidemiological comorbidity, inciting debate about their etiologic overlap

MEG-BIDS, the brain imaging data structure extended to magnetoencephalography
The Brain Imaging Data Structure (BIDS) is an emerging standard for the organisation of neuroimaging data

Role Schizophrenia Genes Play in Brain Development Discovered
A new USC study reports researchers have discovered 150 proteins that affect brain development and cell activity, contributing to the development of mental health disorders

The Making of a Brain
A new study provides novel insight into the development of the mammalian cerebral cortex

Waves Move Across the Human Brain to Support Memory
Alpha and theta oscillations move rhythmically across the brain, reflecting neural activity propagating across the cortex to help form working memory

Maps Made of Nerve Cells
The new model explains how neural activity in the hippocampus can help map space, time and context in episodic memories

Protein Pair Quickly Makes Memories of New Places
A new study reveals how neurogranin and FMRP help encode memories of new places

Brain Area Involved in Understanding Social Interactions Identified
Researchers implicate the posterior superior temporal sulcus in our ability to process social interactions efficiently

Myelin Continues to Grow Throughout Life
Researchers report myelin continues to form and restructure in the adult brain

Democratizing Science: Researchers Make Neuroscience Experiments Easier to Share and Reproduce
Researchers have developed an open access browser that allows display, sharing and analysis of MRI data.

Making New Memories is a Balancing Act
According to researchers, some synapses get smaller as we learn new information

Brain Connections in Schizophrenia
Researchers report reduced connectivity between the thalamus and prefrontal cortex may be a common feature in those with Schizophrenia

Memories Can Be Decoded from Brain Waves During Sleep
Sleep spindles assist with the processing of relevant memories during sleep and help boost memory consolidation

Brain Activity at Rest Provides Clue to Intelligence
A new study reports our level of brain activity while at rest is linked to our ability to perform well in cognitive tests

Researchers Find Algorithm for Large Scale Brain Simulations
Researchers have developed a new algorithm which can speed up brain simulations on supercomputers

Birth of New Neurons in the Human Hippocampus Ends in Childhood
Although observed in other species, researchers report hippocampal neurogenesis does not persist through adult life in humans. Researchers say human hippocampal neurogenesis is not detectable in the adult brain

Diversity of Cortical Neurons Captured in Comprehensive Computer Model
Allen Institute researchers have produced a collection of computer generated models that accurately replicate cortical neuron activity

What Happens in the Brain During Unconsciousness?
Researchers investigate how brain networks fragment while under a variety of unconscious states ?

Genetics Study Closes in on Schizophrenia
Researchers have identified 50 new gene regions they say increase the risk of developing schizophrenia

Seeing the Brain’s Electrical Activity
A new optogenetics approach allows the imaging of neurotransmission without the use of electrode

New Insights On the Neurobiology of Dying
A new study sheds light on the neurobiological processes that occur when we die

Brain Signal that Indicates Whether Speech Has Been Understood Discovered
Using EEG technology, researchers have discovered a specific brain signal that helps us to understand what we hear in conversation

How the Brain Tells Our Limbs Apart
Researchers have identified contrasts in interneurons that govern motor control

Schizophrenia is a Side Effect of Human Development
Researchers have identified altered gene expression in the prefrontal area of the brain in those with schizophrenia. The study reports schizophrenia may have evolved as ‘side effect’ of human brain development

Movie Memento Uncovers How the Brain Remembers and Interprets Events From Clues
Using the movie Memento, researchers discover how the brain creates memories to piece together complex storylines

When it Comes to Our Brains, There’s No Such Thing as Normal
When it comes to the brain, there is “no fixed normal”, researchers say

Electrical Implant Reduces ‘Invisible’ Symptoms of Man’s Spinal Cord Injury
Epidural stimulation has helped improve some of the ‘hidden’ effects, such as abnormal blood pressure and bladder dysfunction, in a patient with spinal cord injury

Newborn Babies Who Suffered Stroke Regain Language Function in Opposite Side of Brain
According to researchers, following a perinatal stroke that damages the language area in the left hemisphere, the brain remaps to use the right hemisphere for language

Pioneering Technique Helps People with Schizophrenia Control Brain Activity
Researchers have developed a new technique that could allow those with schizophrenia, who do not respond to medications, to control verbal hallucinations

Love and Fear Are Visible Across the Brain, Not Restricted to One Region
A new study reports basic emotions, such as happiness and anger, are not limited to specific regions, but have distinct connectivity patterns that encompass much of the brain

Birds and Primates Share Brain Cell Types Linked to Intelligence
Researchers reveal that, while the anatomical structures of bird, reptile and mammalian brains differ, all contain certain types of cells linked to cognitive ability

How Your Brain Helps You Learn New Skills
A new study reveals how fast spiking interneurons improve the efficiency of learning a new skill

Shedding Light on Genetic Overlap Between Major Psychiatric Disorders
Researchers have identified a range of psychiatric disorders, including schizophrenia and autism, that share physical characteristics at the molecular level. Specifically, the study identifies common patterns of neural gene expression. In addition, researchers note important differences in gene expression that distinguish the disorders

How the Brain Constructs the World
Two new studies shed light on the processes that underlie the integration and storage of sensory information

A new study reveals a diverse array of genetic changes that occur in the brain following sensory experiences

The Molecular Mechanisms Behind Memory Formation
Researchers have identified a cellular pathway that encodes memories by strengthening specific neurons

Distinctive Brain Patterns Help Habits Form
MIT researchers have identified neurons that fire at the start and conclusion of a behavior as it becomes a habit

Full Length Serotonin Receptor Structure Seen For First Time
Researchers have been able to view the full length of serotonin receptors for the first time, with the help of Nobel prize winning microscope technology. The snapshot of the receptor includes details of molecular binding sites that could help with the development of a range of new drugs

Dim Light May Make Us Dumber
A new study reveals exposure to dim light might impact memory and learning. Researchers report rodents exposed to dim lighting lost 30 percent of hippocampal capacity and performed poorly on spatial tasks they had previously experienced

New Insights into Autism Spectrum Disorder
Researchers report exposure to a compound used to treat seizures and migraine can cause characteristics associated with autism

Epilepsy Linked to Brain Volume and Thickness Differences
UCL researchers report epilepsy is associated with gray matter differences in thickness and volume in several brain regions

The Creative Brain is Wired Differently
Synchrony between the default mode network and executive control network appear to play an important role in creativity, Harvard researchers report

Friends’ Genes May Help Others Stay in School
Stanford researchers report it’s not just your DNA that influences your educational achievement. The genetics of others in your social circle also influences how far you go in school

Nearly Imperceptible Fluctuations in Movement Correspond to Autism Diagnoses
Movement could be an accurate biomarker for the diagnosis of autism, researchers report

Researchers turn to neuroscience to help explain why some people are more creative than others

Blind in the Mind: Why Some People Can’t See Pictures in their Imagination
Researchers report on why some people experience aphantasia, the inability to imagine in images

Rare Form of ‘Thunder’ Protein May Be Linked to Schizophrenia
A new study has identified rare genetic variation in the Thorase protein that causes the breakdown of receptors at the connections between neurons in the brain. The anti-epilepsy drug perampanel can help reverse anti-social behaviors linked to schizophrenia that are associated with this genetic variation.

Layer-specific modulation of neocortical dendritic inhibition during active wakefulness
Specialized nerve cells, known as somatostatin-expressing (Sst) interneurons, in the outer part of the mammalian brain - play a key role in controlling how information flows in the brain

Ultrastructural evidence for synaptic scaling across the wake/sleep cycle
The axon-spine interface decreased ~18% after sleep compared with wake

Study Shows How Epilepsy Drugs Block Electrical Signals in the Brain
A new study reports computer simulations have helped to identify the drug’s binding site

The Rhythm That Makes Memories Permanent
Sharp wave ripples, brain waves important for memory consolidation, are influenced by synaptic inhibition.

‘Latest Spoke in the Wheel’ Drives Brain-Mapping Advances
A special section on “Super-resolution Microscopy of Neural Structure and Function” in the current issue of the journal Neurophotonics

New Mechanism of How Brain Networks Form Identified
Excitatory neurons sculpt and refine maps of the external world throughout development and experience, while inhibitory neurons form maps that become broader with maturation

The Last Frontier: The Molecular Basis of Brain Plasticity and How Neurons Learn
A new study proposes a new theory to how neurons learn

Further Evidence for Causal Link Between Schizophrenia and Cannabis
Schizophrenia risk may predict cannabis use, rather than the other way around

Mapping the Brain’s Aging Connections
Impact of ageing on brain connections mapped in major scan study

Non-Invasive Brain Stimulation Improves Cognitive Control
Applying transcranial direct current stimulation to the dorsolateral prefrontal cortex can help to improve cognitive control and may be a beneficial treatment for those with autism, schizophrenia and ADHD

Researchers Make an Autism Breakthrough
As many as a third of autism cases could be explained by a scarcity of a single protein in the brain

Teens Benefit From Later High School Start Times
Later high school start times are associated with reduced motor vehicle accidents and less daytime sleepiness for teens

Researchers Identify New Epilepsy Gene Network
Researchers have identified a network of 320 genes they believe to be associated with epilepsy

Neuromotor Problems At the Core of Autism
Researchers warn using psychotropic medications to treat autism could make neuromotor problems worse

Study Uncovers Details of Information Processing in the Brain
New research shows that, when focused, we process information continuously, rather in waves as previously thought

Illusion Reveals the Brain Fills in Peripheral Vision
What we see in the periphery, just outside the direct focus of the eye, may sometimes be a visual illusion

How the Hippocampus Influences Future Thinking
Researchers report the hippocampus isn’t just important for remembering past events, it also plays a vital role in future planning

Selective modulation of cortical state during spatial attention
Cortical states are controlled locally within a cortical map according to cognitive demands

Brain Connections Show More Symmetry Between Hemispheres in People With Autism
A new study identifies differences in brain connectivity in people with ASD compared to their typically developing peers

Researchers use fast fMRI to track the brain activity that occurs during thought

Brain Pattern Flexibility and Behavior
Researchers investigate how high level cognitive processing occurs by looking at how different brain regions are connected

3D embryo atlas reveals human development in unprecedented detail
Digital model will aid vital research, offering chance chance to explore intricate changes occurring in the first weeks of life

A computer program just ranked the most influential brain scientists of the modern era
1st Karl J. Friston, 2nd Raymond J. Dolan, 3rd Marcus E. Raichle

A dinosaur’s brain, preserved in a pebble
The first known evidence of fossilized brain tissue of a dinosaur

Big dreams emerge for big brain science projects
The United Nations of Brain Projects met nearby in unbounded enthusiasm for the idea that transnational cooperation will, at last, explain the brain

This protein designer aims to revolutionize medicines and materials
Baker’s team and collaborators report making cages that assemble themselves from as many as 120 designer proteins, which could open the door to a new generation of molecular machines

How Words Are Represented in the Brain
A new study sheds light on the neurobiology of reading.

Updated human brain map reveals nearly 100 new regions
The Human Connectome Project defined 180 distinct areas, including nearly 100 that have never been described before

Imaging synaptic density in the living human brain
Scientists developed a noninvasive approach to “see” human synapses by using an imaging agent that targets the synaptic vesicle glycoprotein 2A (SV2A).

Unlocking the Secrets of the Brain: Defining and Measuring Human Intelligence
Researchers have identified how different parts of the brain interact with each other at different times in order to discover how intellect works

Tau protein—not amyloid—may be key driver of Alzheimer’s symptoms
A new imaging study of 10 people with mild AD suggests that tau deposits—not amyloid—are closely linked to symptoms such as memory loss and dementia

How the Brain Switches to Memory Mode
Certain cells in the brain, the hippocampal astrocytes, ensure that the new information is given priority

Consciousness Harmed by Abnormal Brain Interactions
There are two networks related to the perception of either the external world or internal thoughts

Simpler Nervous Systems 2016
XI East European Conference of the International Society for Invertebrate Neurobiology 05.16-05.19.2016

Sleep deprivation impairs learning and memory
Sleep deprivation impairs memory by attenuating mTORC1-dependent protein synthesis

Newborn neurons keep memories crisp and fresh
Nestled deep within a brain region that processes memory is a sliver of tissue that continually sprouts brand-new neurons, at least into late adulthood

Illuminating Pathways of Neurological Disorders
Scientists have now described the engineering of a bright red fluorescent protein-based voltage indicator, providing pathways to understanding complex neurological disorders

Do I Like You? Subconscious Evaluation of Social Groups Occurs in Milliseconds
Freiburg scientist has decoded brain processes associated with the subconscious evaluation of social groups

Poor Short Term Memory Linked to Inability to Ignore Distractions
An individual’s working memory capacity correlate with the brain’s ability to actively ignore distraction

Understanding Consciousness Disorders
A bedside device that measures ‘brain signatures’ could help diagnose patients who have consciousness disorders

Barcoding the brain
IARPA funds effort to map synaptic connections

Lifelong memories may reside in nets around brain cells
Studies suggest key role for perineuronal networks of proteins and sugars in long-term memory

Alzheimer’s disease tied to brain’s navigation network
The way you navigate a virtual maze may predict your chances of getting Alzheimer’s

Wired for Cognitive Control
How does the brain determine which direction to let its thoughts fly?

Memory consolidation by gene suppression
The suppression mechanisms in the hippocampus appear to play a major role during memory consolidation

Dopamine and serotonin signals for reward across time scales
Neurons that release different neurotransmitters transmit different information aboutrewards

Slow or fast? A tale of synaptic vesicle recycling
A new model accounts for synaptic transmission speed

Brain crystals
Our brains may perceive distance differently in environments with polarized geometry

Observing Motor Neurons Walking in Real Time
Researchers develop a method to observe the activity of motor neurons in real time

Shorter School Week Improves Academic Performance
Shortening the school week to four days has a positive impact on elementary school students’ academic performance in mathematics

Predicting Response to Antipsychotic Medications with Neuroimaging
Investigators at The Feinstein Institute for Medical Research have discovered that brain scans can be used to predict patients’ response to antipsychotic drug treatment

Giving Paralyzed People a Voice
New technology allows paralyzed people and those with locked in syndrome to communicate by using their breath

Brain Structure Differences Suggest Teens May Not ‘Grow Out of’ ADHD
Young adults diagnosed with attention deficit/hyperactivity disorder (ADHD) in adolescence show differences in brain structure and perform poorly in memory tests compared to their peers

Automated Speech Analysis Program Can Identify People at Risk for Psychosis
An automated speech analysis program correctly differentiated between at-risk young people who developed psychosis over a two-and-a-half year period and those who did not

Lower Vitamin D Levels Associated with Higher Risk of Multiple Sclerosis
According to a new study, genetic findings support observational evidence that lower vitamin D levels are associated with increased risk of multiple sclerosis

Study Shows ‘Smart Drug’ Modafinil Does Enhance Cognition
A new study reports modafilnil, a drug developed to treat narcolepsy and often touted as a 'smart drug', actually does provide cognitive benefits, at least for a particular subset of skills

Reprogramming Cancer Cells Back to Normal Cells
Cancer researchers dream of the day they can force tumor cells to morph back to the normal cells they once were

Surprising Link Between TBI and ADHD
A new study has found a “significant association” between adults who have suffered a traumatic brain injury at some point in their lives and who also have attention deficit hyperactive disorder

Break in Working Relationship Between Two Trash Clearing Proteins May Result in Parkinson’s Disease
Two proteins that share the ability to help cells deal with their trash appear to need each other to do their jobs and when they don’t connect, it appears to contribute to development of Parkinson’s disease

Researchers Visualize Critical Part of Basal Ganglia Pathways
Researchers use neuroimaging technology to visualize the pathways that connect the different areas of the basal ganglia. The research could lead to new tracking of disease progression in Parkinson's and Huntington's disease

Mechanism that Triggers Disruption in Neural Communication Channels in Schizophrenia Identified
Researchers have identified a mechanism which triggers the disruption in the brain's communication channels that occurs in schizophrenia.

Exploring the Relationship Between Autism and Creativity
New research has found that people with high levels of autistic traits are more likely to produce unusually creative ideas

Uncovering the Neurological Differences Between the Sexes
Researchers have discovered biological differences between males and females in the molecular regulation of synapses in the hippocampus.

Eye Movements During REM Sleep Reflects Brain Activity Associated with New Images
A new study offers evidence between rapid eye movement during sleep, accelerated brain activity and dream images.

Shedding Light on Why We Trust
Researchers shed new light on the neurobiology of why people trust one another.

Novel Memory Pathway Helps Us Recognize What’s New and What’s Familiar
Researchers have identified a novel neural network which processes incoming information based on whether it’s something we’ve experienced previously or not


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